Spandan Critical Care & ICU

Uncategorized

The Intestinal Microbiome in Critical Illness

The intestinal microbiome is comprised of diverse, robust microbial communities within the intestine, modified by the host’s interaction with the environment (Amon and Sanderson 2017). Increasingly, research links alterations in the microbiome to maintenance of health and pathophysiology of disease. Critical illness is no exception. Given the lack of therapies aimed at the host response …

The Intestinal Microbiome in Critical Illness Read More »

Microbiome in Critical Illness

Multiple factors can bring the microbiome out of balance in critically ill patients in the intensive care unit. These include antibiotic use, mechanical ventilation, changes in diet and inflammatory responses. The dysbiosis of the microbiome can alter immunological responses and could potentially have an impact on patient outcomes. There are approximately 100 billion microorganisms in our body. …

Microbiome in Critical Illness Read More »

Microbiome in Sepsis and COVID-19

Introduction Bacteria play, for better or worse, a fundamental role in human life. As multidrug resistant bacterial infections are increasing in incidence and mortality, we often consider only the negative impact of bacteria on human life and forget the positive side of the “bacterial coin” – the microbiota. Commensal microbes are critical components that contribute …

Microbiome in Sepsis and COVID-19 Read More »